Family-friendly vacation rentals in James Island
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in James Island
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island family-friendly rentals
Family-friendly home rentals with a hot tub
Home in Charleston
4.87 out of 5 average rating, 207 reviewsCharleston Tranquil Marshside Retreat w/Pool/Spa
Home in North Charleston
4.97 out of 5 average rating, 253 reviewsHome The On Hill - Near Everything Charleston!
Home in Charleston
4.84 out of 5 average rating, 430 reviewsBest of Both Worlds with Beautiful Back-Yard Oasis
Cottage in Isle of Palms
4.95 out of 5 average rating, 109 reviewsCharming Cottage at Beach with Golf Cart
Island in Isle of Palms
4.86 out of 5 average rating, 187 reviewsSummer Hayes on IOP with extra special Pool
Townhouse in Folly Beach
4.87 out of 5 average rating, 76 reviews121 E Ashley - The Blue Crab - Renovated in 2024
Condo in Folly Beach
4.82 out of 5 average rating, 68 reviewsThe BEST Balcony On Folly Beach!
Bungalow in Isle of Palms
4.93 out of 5 average rating, 27 reviews4 BedroomBungalow with Huge Private Pool
Family- and pet-friendly home rentals
Guest suite in Charleston
4.92 out of 5 average rating, 342 reviewsIsland Hideout
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 217 reviewsBungalow Under The Oaks
Home in Charleston
4.86 out of 5 average rating, 274 reviewsCentral Island Home
Cottage in Johns Island
4.9 out of 5 average rating, 209 reviewsLi'l Blue Cottage - NO PET FEE!
Guesthouse in Summerville
4.98 out of 5 average rating, 651 reviews★Delightful guest house near historic plantations★
Guest suite in Charleston
4.95 out of 5 average rating, 650 reviewsWest Ashley Semi Detached Private Guest Studio
Home in Charleston
4.81 out of 5 average rating, 421 reviewsCharming 1BD with parking!
Guest suite in Mount Pleasant
4.89 out of 5 average rating, 315 reviewsCathy’s Conch House. Pets welcome
Family-friendly home rentals with a pool
Guesthouse in Charleston
4.84 out of 5 average rating, 112 reviewsRomantic Beach Style Cottage close to everything!
Cottage in Mount Pleasant
4.96 out of 5 average rating, 350 reviewsWalk to Shem Creek! & Bike to BEACH
Condo in Charleston
4.93 out of 5 average rating, 110 reviewsFolly Beach sunrise and sunsets
Apartment in Johns Island
4.95 out of 5 average rating, 204 reviewsSailors Rest: Heated Pool & Sauna, Johns Island
Apartment in Folly Beach
4.96 out of 5 average rating, 351 reviewsWater life “Aquavida”
Apartment in Charleston
4.78 out of 5 average rating, 454 reviewsCourtyard Suite with Tranquil Garden & Heated Pool
Home in Mount Pleasant
4.94 out of 5 average rating, 210 reviewsCoastal Family Getaway, Heated Pool
Cottage in Mount Pleasant
4.96 out of 5 average rating, 139 reviewsBreezy Poolhouse Cottage
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- Family travel hub Tips and inspiration
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