
Vacation rentals in Santee River
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santee River
Guests agree: these stays are highly rated for location, cleanliness, and more.
0 of 0 items showing
1 of 3 pages
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santee River vacation rentals
Other great vacation rentals in Santee River
Guest favorite

Home in Summerton
4.83 out of 5 average rating, 108 reviewsPerfect family vacation retreat at Lake Marion, SC
MichaelRating, 5 stars2 weeks ago
We had a great weekend! The house was great as well as the outdoors. We enjoyed fishing and having the private dock. We also enjoyed the fire pit. Andrea was an excellent host and we strongly recommend this listing. Thanks again Andrea!
Superhost

Home in Isle of Palms
4.67 out of 5 average rating, 24 reviews8 44th- Family Beach House, Partial Ocean Views!
PatriciaRating, 5 stars4 months ago
Felt very welcome as host was pleasant and accommodating . The house is spacious and well kept. I would definitely come back again.
Top guest favorite

Home in Summerton
5 out of 5 average rating, 15 reviewsAlmost Heaven on Lake Marion, SC
GlendaRating, 5 stars1 week ago
My family had an amazing stay for spring break! The pictures really do not do this place justice. The home’s layout is spacious and the kitchen is stocked with all the necessities. The back porch is huge and looks onto the lake. The private beach area is perfect for laying out and there are plenty of chairs. We used the dock for fishing and were able to rent a pontoon boat that we tied up to the dock for easy access. Audrey was very responsive and helpful with any questions that we had. I would definitely rent this place again!
Top guest favorite

Home in Manning
5 out of 5 average rating, 28 reviewsLakeside Hideaway
KatrinaRating, 5 stars1 month ago
Heather is an amazing host. She made us feel as if we were home. It was so comfortable, and cozy. I would absolutely highly recommend staying here. We will definitely come back, and stay here again. Thank you for everything Heather.
Superhost

Condo in Isle of Palms
4.82 out of 5 average rating, 17 reviews#107 Cozy Corner, 2br/2ba
JeanetteRating, 5 stars13 months ago
My expectations were surpassed! Loved staying here for the few days we were in Isle of Palms. It is the perfect walking distance from the beach and has everything you’ll need for your stay! It did take us a couple tries to understand the lock but we are thankful for that note so we didn’t freak out! Lol thank you!

Condo in Isle of Palms
4.92 out of 5 average rating, 176 reviewsOcean Breeze Villa
PattyRating, 5 stars2 weeks ago
Great location…. Loved hearing the ocean. Donna was quick to respond on any issues. Great place to stay!
Top guest favorite

Home in North Charleston
5 out of 5 average rating, 56 reviewsPool | Charleston | Near Airport, Downtown & Beach
ChristopherRating, 5 stars1 week ago
I met with some friends from all over North America, and they all had an amazing experience. Renee was proactive in trying to solve potential issues and was very friendly! Highly recommend to anyone looking for a comfortable stay in Charleston!
Superhost

Apartment in Isle of Palms
4.74 out of 5 average rating, 200 reviewsCozy Beachside Retreat
TamalaRating, 5 stars3 weeks ago
Very short walk to the beach. Located in Wild Dunes, this condo unit is at the far end of the island, and we had tons of space on the beach. You also get access to the pool and golf course. Uber/Lyft readily available for transportation to downtown or across the bridge to Charleston. The condo itself is basic so if you need extra towels, pillows, and blankets, bring them. Overall a great value for the weekend stay.
Destinations to explore
- Hilton Head Island Vacation rentals
- North Myrtle Beach Vacation rentals
- Columbia Vacation rentals
- Folly Beach Vacation rentals
- Mount Pleasant Vacation rentals
- Atlanta Vacation rentals
- Gatlinburg Vacation rentals
- Charleston Vacation rentals
- Western North Carolina Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Outer Banks Vacation rentals
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Garden City Beach
- Sullivan's Island Beach
- Huntington Beach State Park
- White Point Garden
- Middleton Place
- Love's a Beach
- Angel Oak Tree
- Yeamans Hall Club
- Hampton Park
- Shem Creek Park
- Caledonia Golf & Fish Club
- The Charleston Museum
- Magnolia Beach
- Waterfront Park
- Litchfield Beach and Golf Resort
- The Golf Club at Wescott Plantation
- Sandy Point Beach
- Pawley's Island parking lot South
- Gibbes Museum of Art
- Morris Island Lighthouse
- Palm Plantation
- Captain's Quarters Building C - Litchfield By The Sea
- Isle of Palms Beach
- Whirlin' Waters Adventure Waterpark
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes