Guesthouse vacation rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Chula Vista
4.95 out of 5 average rating, 476 reviewsPrivate Casita in Great Eastlake Neighborhood
Oct 22 – 29
Guesthouse in La Jolla
4.78 out of 5 average rating, 600 reviews$100-150 night--Windansea #3
Nov 14 – 21
Guesthouse in San Diego
4.97 out of 5 average rating, 292 reviewsPrivate Guest House with a View
Aug 8 – 15
Guesthouse in Encinitas
4.86 out of 5 average rating, 228 reviewsSunset/Ocean View Guest House! Minutes to Beach
Sep 25 – Oct 2
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Oct 29 – Nov 5
Guesthouse in El Cajon
4.98 out of 5 average rating, 190 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Mar 23 – 30
Guesthouse in San Diego
4.98 out of 5 average rating, 133 reviewsPeaceful Mariposa Casita with Private Patios
Apr 2 – 9
Guesthouse in La Mesa
4.92 out of 5 average rating, 206 reviewsFig Tree Bungalow
Aug 13 – 20
Guest house rentals with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 107 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Oct 25 – Nov 1
Guesthouse in Lakeside
4.94 out of 5 average rating, 100 reviewsSky Mesa-Adorable Cottage on the Hill
Jan 26 – Feb 2
Guesthouse in San Diego
4.98 out of 5 average rating, 124 reviewsPrivate Studio Cottage with Outdoor Patio
Dec 24 – 31
Guesthouse in La Mesa
4.98 out of 5 average rating, 250 reviewsLa Mesa Suite
Feb 25 – Mar 4
Guesthouse in San Diego
4.92 out of 5 average rating, 150 reviewsCentral studio w/ private outdoor space & parking
Mar 22 – 29
Guesthouse in San Diego
4.96 out of 5 average rating, 103 reviewsCozy Urban Casita! Near Zoo, Gaslamp and Coronado
May 13 – 20
Guesthouse in Spring Valley
4.97 out of 5 average rating, 112 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
May 31 – Jun 7
Guesthouse in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
Feb 1 – 8
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.87 out of 5 average rating, 418 reviewsThe Golden Hill mosaic "casita"
Jul 7 – 12
Guesthouse in San Diego
4.9 out of 5 average rating, 193 reviewsSTUNNING Casita with a View!!
Oct 18 – 25
Guesthouse in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
Sep 10 – 17
Guesthouse in San Diego
4.91 out of 5 average rating, 151 reviewsRelaxing Oasis - short walk to shops & recreation
Oct 19 – 26
Guesthouse in San Diego
4.95 out of 5 average rating, 109 reviewsRelax in a Centrally Located, Modern Guest House
Oct 14 – 21
Guesthouse in San Diego
4.97 out of 5 average rating, 306 reviewsPrivate Guesthouse in Trendy North Park
Nov 2 – 9
Guesthouse in San Diego
4.99 out of 5 average rating, 131 reviewsCarrie’s North Park Casita, in Heart of San Diego
Sep 11 – 18
Guesthouse in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
Oct 13 – 20
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
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