Vacation rentals in Mira Mesa, San Diego

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Top-rated vacation rentals in Mira Mesa, San Diego

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Rancho Bernardo

4.92 out of 5 average rating, 655 reviews

Hilltop cabin retreat with lake & mountain views

Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

Guest favorite

Tiny home in La Mesa

5 out of 5 average rating, 105 reviews

Casita de Pueblo - Private Yard, La Mesa Village

Enjoy a stylish experience at this centrally-located studio. Walking distance to La Mesa Village, where you can enjoy restaurants, coffee shops, boutiques, & more. With all the things you need in a kitchen to whip up any meal, and a patio to enjoy the San Diego sun. Hop on the trolley to get to anywhere. Bringing more friends or family along with you? We also have another listing, Casa de Pueblo at the same property. 20 min drive to the Beach or Downtown 15 min drive to Balboa Park or Old Town

Guest favorite

Guest suite in Serra Mesa

4.96 out of 5 average rating, 194 reviews

Urban Retreat

Modern one bedroom unit, with private entrance. Attached to the main house. Heat and air conditioning. Private backyard. Hot tub available upon request. The neighborhood is very quiet, providing a relaxing stay in a comfortable, clean setting. It is ideally located centrally to many attractions, such as beaches, San Diego Zoo, Balboa Park, and Sea World, all of this places are about a 15-20 minute drive. It’s great for 2 guest. But sofa bed in the living room can accommodate +2 *extra fees

Guest favorite

Guest suite in San Diego

4.96 out of 5 average rating, 334 reviews

Private Studio 15 min to the Beach w/ backyard

CENTRAL & VERY PRIVATE! 15 min to the beach, stylish, bright, and inviting studio is filled w/ amenities & hosted with 5 Star Experience. Perfect for couples, small families, business travelers, and solo adventures. The vibe is a brilliant mashup of European sophistication, West African artifacts & Brazilian charisma. The 5 C’s Studio, hits all your senses - sparkling CLEAN. CENTRAL to all attractions. CLASSY, and CALMING for all. In the heart of CALIFORNIA’s finest city! BEACH GEAR PROVIDED!

Guest favorite

Rental unit in Serra Mesa

4.97 out of 5 average rating, 316 reviews

Anna’s modern & private San Diego guest studio!

Welcome to Anna's Getaway! Recently updated, beautifully detailed, clean, modern & spacious studio, private entrance, patio, A/C & heating, Tesla Solar System & plenty street parking! High ceilings! Family friendly: Infant travel crib, high chair, toys & baby items. WiFi, Netflix and cable TV. Fully equipped kitchenette. Shower & bathtub. Washer & dryer. Centrally located in a quiet, safe & peaceful neighborhood, walking distance to playgrounds & parks! Whole house water filtration system!

Guest favorite

Guesthouse in San Diego

4.9 out of 5 average rating, 160 reviews

Central studio w/ private outdoor space & parking

Studio unit with ample street parking in safe quiet neighborhood. Private entrance with outdoor space, fenced in and safe for pets. Updated kitchen/bathroom with a clean bright living space. Everything is brand new within the unit (linens, towels etc.) Close to the freeway, very easy access to all major SD attractions without the hassle of traffic! Pacific Beach: 3.6 miles La Jolla Shores: 3.7 miles Airport: 7.3 miles Little Italy: 7.4 miles Balboa Park: 7.8 miles SD Zoo: 7.4 miles

Guest favorite

Guest suite in Allied Gardens

4.92 out of 5 average rating, 110 reviews

Beautiful Studio w/Private Kitchenette & Bath

Large 500 square foot studio apartment. Lots of natural light and open concept, perfect for small families or friends traveling to San Diego. Fully functioning and well stocked kitchenette with microwave, stovetop, toaster, and coffee maker. One queen bed plus a sofa bed couch. Large newly remodeled master bathroom. Large walk-in closet with dresser. Plenty of space for one or two air mattresses. The neighborhood is quiet and safe. Private entrance to come and go any time of the day.

Guest favorite

Rental unit in Serra Mesa

4.98 out of 5 average rating, 408 reviews

Lovely spacious upstairs studio with private entry

You’ll love our place as its spacious, quiet, private, comfortable in a residential neighborhood. The king-size bed is extremely comfortable and we have big relaxing patio chairs on our large balcony overlooking a beautiful landscaped garden. We are centrally located to most all of San Diego's attractions and close to freeways. The famous Gaslamp, Zoo, downtown and beaches are all within 13 to 20 minute drive. The kitchen is stocked with goodies, coffee and an assortment of teas.

Guest favorite

Guesthouse in Mira Mesa

4.95 out of 5 average rating, 119 reviews

Adorable studio/private entrance/reserved parking

New constructed studio with private entrance and 1 reserved drive way parking spot in an upscale neighborhood. Bright color designs will bring you good mood and energy. Neighborhood is quiet and safe, near Sorrento valley, La Jolla and Del Mar beach. So many good restaurants and markets around. I'm an interior designer and really care about how my guests feel during their stays. When I designed and built this unit, I choose all unique materials that bring you the best experience.

Guest favorite

Guest suite in Del Cerro

4.97 out of 5 average rating, 154 reviews

Guesthouse near SDSU in Upscale Area - Cal King

Our professionally cleaned Studio Guest House comes complete with kitchenette, dining and sitting area, and a Sealy Posturepedic cal king bed. At 360 square feet, the guesthouse is attached to our main house where we live and has a private entrance with self-check in and no shared access. It's the perfect place to wind down from your days adventure; conveniently located near SDSU in a safe, quiet family neighborhood. All San Diego attractions are only a short drive away.

Guest favorite

Rental unit in Solana Beach

4.89 out of 5 average rating, 140 reviews

Designed, Renovated Spacious Solana Surf Loft!

Artistically renovated, spacious studio loft with high end finishes and professional design by Solstice Interiors. Location can't be beat! Ocean breeze and short walking distance to Solana Beach's amazing shopping, restaurants, breweries, bars, grocery, the Cedros Ave Design District. Dedicated router within your space for your exclusive use and professional level customer service plan to address any ISP errors immediately. Perfect place to work remotely!

Guest favorite

Tiny home in Rancho Penasquitos

4.91 out of 5 average rating, 170 reviews

WOW! Private Studio Minutes To Shopping& Freeways.

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 bath. Ideal for couples, solo adventurers, and business travelers. Studio is fully equipped with 1 queen bed, 1 working desk, kitchenette meant for light food warm, mini size refrigerator, single sink meant for light cup and dish wash. All new furniture, mattress, beddings. All shops, restaurants, cinema, hiking trails within minus drive about 1-5 miles away!