Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Mesa

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Mesa

4.99 out of 5 average rating, 170 reviews

Hideaway- Pool, Hot tub, Bikes, Near Hiking, Lakes

Midcentury guest house situated on the base of a mountain. 1.6 acre property near the Superstition Mountains. Pool, Hot tub, Mountain bikes or Beach Cruisers. 850 sq. ft. 1 bedroom, 1 bath, full kitchen, desk area - work space with great WI FI, washer, dryer, wood burning stove. Tastefully decorated with local artwork. Great location for hiking and biking. Our home is situated on the slope of a mountain and guest house is down below. Private with carport and covered patio with Barbeque Grill.

Guest favorite

Guesthouse in Mesa

4.92 out of 5 average rating, 372 reviews

The Oasis Hideout

Welcome to our delightful, hidden oasis in the Valley of the Sun! •A 10-minute walk from the light rail station for convenient access to the downtowns of Phoenix/Tempe/Mesa, Sky Harbor Airport, ASU, and Mill Ave •Kingsdown luxury mattress with adjustable base •Fast 1-Gbps WiFi & Chromecast TV for use with your streaming accounts •Refreshing 9' deep diving pool •Enjoy some R&R lounging in the hammock, sipping drinks, or watching the dusk fade around the firepit .Due to allergies, no pets,please

Guest favorite

Guesthouse in Phoenix

4.98 out of 5 average rating, 882 reviews

Boutique Hotel Style Guest House

Let us make you feel pampered in our beautiful, comfortable, pet-friendly, stand-alone casita with its own private courtyard. The 225 sq. ft. guest house is in a great foothills neighborhood with many shops, restaurants, and leisure activities close by. Easy access to most of Phoenix's attractions. We provide a complimentary bottle of wine, bottled water and snacks to enjoy during your stay. No minimum stay, cleaning or pet fee. Owner occupied property Contactless check-in and check out.

Guest favorite

Guesthouse in Gilbert

4.93 out of 5 average rating, 226 reviews

Private Cozy Cottage in Gilbert. Close to it all!

Recently updated- the Cozy Cottage is perfect for your AZ stay and has everything needed to make your trip as comfortable as possible. Ideal for couples and young families. Safe for solo travelers. The neighborhood is upscale and a great location. Walk to the Gilbert Riparian a nature lovers paradise just 1/4 mile away. Shopping, restaurants, nightlife are 10 minutes away. 20 mins to Phx, Scottsdale or desert hiking. We are here to answer any questions or help with any issues 24/7.

Guest favorite

Guesthouse in Gilbert

4.99 out of 5 average rating, 223 reviews

TnT Family Farm Guest House

Private guest house on a nonsmoking property with galley kitchen, full bath and walk in closet. Fully furnished and equipped, located on site at TnT Family Farm, a gated hobby farm. Well behaved dogs and declawed cats welcome. Due to space, only two animals are permitted - see house rules before instant booking. Easy Interstate 60 & Loop 202 access. Close to Gateway Banner Hospital, AT Stil University, ASU Polytech, Mesa Gateway & Sky Harbor International Airports.

Guest favorite

Guesthouse in Mesa

4.95 out of 5 average rating, 128 reviews

Private Entry Detached Guesthouse w/ Free Parking!

Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Guest favorite

Guesthouse in Mesa

4.98 out of 5 average rating, 123 reviews

Entire Suite:Private and Cozy Clark House Casita

Enjoy your stay at our unique 350 sq ft casita! It is partially attached to the main house, but has its own entryway for total privacy. The space has a full bathroom and a kitchenette. Rest easy on the comfortable queen size bed while catching up on your favorite Netflix series on the HD smart tv, or relax in the shaded patio surrounded by mature trees. You will have access to a covered parking space in the carport. No smoking or vaping on or inside the property.

Guest favorite

Guesthouse in Mesa

4.87 out of 5 average rating, 276 reviews

Casita/ Heated Pool, Hot Tub, Amazing Amenities

Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Guest favorite

Guesthouse in Chandler

4.93 out of 5 average rating, 190 reviews

Stylish Studio

Private guest house tucked away from the hustle and bustle. New AC unit! Enjoy the clean and bright space with a full kitchen, comfortable bed, and comfy couch. Enjoy a cool drink on your private porch. Minutes away from the airport (12 min), shopping (5min), Tempe Town lake (10 min), Scottsdale (10 min) and much more. You have full access to the pool and yard. There is no pool fence, so please use caution with small children.

Guest favorite

Guesthouse in Mesa

4.93 out of 5 average rating, 203 reviews

Cozy, Private Mid-Century Casita

Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite Netflix series on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. Please, no children or animals.

Guest favorite

Guesthouse in Mesa

4.97 out of 5 average rating, 211 reviews

Sanitized Spacious Desert Getaway

Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Guest favorite

Guesthouse in Mesa

4.97 out of 5 average rating, 430 reviews

Mesa Casita with King Bed

Casita with a king size bed and kitchenette located in a quiet Mesa neighbored. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.