Guesthouse vacation rentals in Durham

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Durham

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in Fuquay Varina

4.95 out of 5 average rating, 248 reviews

Carriage House at Bracken in Downtown Location

New, private and quiet colonial Carriage House overlooking a park in historic downtown Fuquay-Varina. A lovely half mile walk to both Fuquay and Varina town centers with easy access to eateries, breweries and boutiques. Kitchen has full fridge, microwave, toaster oven, sink, 2 burner cooktop, Keurig with milk frother, coffee and tea supplies, cooking utensils, pots, pans, silverware, breakfast table and chairs. Our place has a queen bed, antique tall boy dresser, oak rocking chair, couch, and TV

Guest favorite

Guesthouse in Raleigh

4.93 out of 5 average rating, 149 reviews

Changes In Latitudes Pool & Suite Raleigh NC.

Your biggest decision will be whether to float in the sparkling salt water pool, relax on your private deck nestled in the woods, or hike the nearby trails. Hang out and cook in your fully-equipped kitchen, grill steaks on your private deck, or go into Raleigh to experience all the amazing delights the city has to offer. Your private escape is next to our home, & we take Southern Hospitality very seriously! Just let us know how we can make your stay perfect! We look forward to meeting you!

Guest favorite

Guesthouse in Holly Springs

5 out of 5 average rating, 103 reviews

"Wit's End" welcomes you! 2BR comfy guest house

Be our guest at Wit's End, a separate 2BR, 1 bath carriage house on our property in Holly Springs. Located in a quiet, safe neighborhood. Handicap-accessible and compliant. Natural light permeates the house in its wooded setting, and it is equipped with new paint, furnishings and linens. Private entrance, dedicated parking spaces, powerful WIFI and a fully-equipped kitchen to provide you with all the comforts of home. Convenient access to Raleigh, Durham, Chapel Hill, and the RDU airport.

Guest favorite

Guesthouse in Raleigh

4.98 out of 5 average rating, 177 reviews

Downtown Private Oasis w/ Cal King

This new apartment is built over our detached garage on the back corner of the property. The private garden walkway will lead you to the entrance where you'll find a wide open space boasting cathedral ceilings, a completely private patio with multiple other outdoor seating areas, quartz countertops, a quiet work space, a huge walk in closet, and a luxury California kind size bed. We're walkable (1 mile) to downtown Raleigh and other shops/ restaurants, close to NCSU, and centrally located

Guest favorite

Guesthouse in Carrboro

4.98 out of 5 average rating, 323 reviews

Cute Downtown Carrboro Studio Cottage

Private studio cottage in downtown Carrboro neighborhood with sidewalks, bike lanes, a block from the free bus. Coffee shop across the street, walking distance to Carrboro and UNC campus. Separate from the main house with its own entrance, outdoor sitting area, small but well-equipped+stocked, clean, efficient, perfectly located. WiFi, 40" TV-Roku, full bathroom, free parking, small kitchenette, queen bed, futon for additional sleeping accommodations, small work station, walk-in closet.

Guest favorite

Guesthouse in Durham

4.98 out of 5 average rating, 107 reviews

Great Guesthouse Studio Suite w/ hot tub & pool!

Book now & enjoy the pool, balcony & luxury high-end hot tub. Open 24hrs, exclusively for guest use. We welcome you to our little piece of paradise, not far from downtown Durham & Raleigh close to RDU. We offer a well-appointed studio, meticulously cleaned, with a queen Tempurpedic mattress, premium linens, fireplace, full kitchen, washer/dryer, 2 smart TV's & high speed wifi. *Please be aware* Due to allergies & health risks, we are unable to accommodate any animals. Sorry :-(

Guest favorite

Guesthouse in Wake Forest

5 out of 5 average rating, 164 reviews

2 BR, 1.5 BA Guest House on 2-acre wooded lot

Relaxing, stress free stay on wooded 2 acre lot. Located 5 minutes from downtown Wake Forest and 25 minutes from downtown Raleigh. Furnished 2 bedroom, 1.5 bath private guest house with fully equipped kitchen. Quiet neighborhood & ample parking. Guesthouse WiFi, Roku tv's & access to home gym. The guesthouse is connected to the host's garage and detached from the main house. A breezeway connects garage to main house, leading to the shared laundry space (located in the main house).

Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 146 reviews

Spotless Scent & Mold-Free Guesthouse Near Duke!

New-construction (2022) spotlessly clean farmhouse-style guesthouse is 3 mins to Duke, 15 mins to UNC and 25 mins to Raleigh. Perfect for an RTP work trip or weekend alumni or family/student visit. Explore Durham (8 min drive to downtown Durham, DPAC, American Tobacco, etc.) or anywhere in the Triangle from this South Durham location in the charming Tuscaloosa-Lakewood neighborhood. Walking distance to Cocoa Cinnamon coffee shop and restaurants serving breakfast, lunch and dinner.

Guest favorite

Guesthouse in Hillsborough

4.96 out of 5 average rating, 354 reviews

Hummingbird Retreat

Airy and open, private and quiet! Come get away from it all and still be a short drive to all that the Triangle has to offer! High quality cottage style carriage house loft with full bath & private entrance - luxurious king-sized bed, Bonavita coffee maker, and handy microwave and mini fridge. Located just 4 miles south of hip and historic downtown Hillsborough in a rural, wooded country setting. Close access to Duke, UNC Chapel Hill; and Elon University is 27 miles west on I40.

Guest favorite

Guesthouse in Apex

4.93 out of 5 average rating, 368 reviews

Country place close to all Triangle locations

Beautiful setting on 8 acres near Jordan Lake and the American Tobacco Trail - 30 minutes or less to RDU, RTP, Raleigh, Durham and Chapel Hill. Full use of a 930 sf guesthouse with a spiral staircase leading to a loft bedroom. Downstairs, soaring 20 foot ceilings and huge windows look out on our pastures, where our horse and pony lounge. Covid precautions include following all AIRbnb protocols.... and just a $25 cleaning fee!

Superhost

Guesthouse in Carrboro

4.85 out of 5 average rating, 428 reviews

Guest cottage close to downtown Carrboro

This comfortable and pretty guest cottage is the perfect base for your visit to Carrboro/Chapel Hill. Relax and enjoy your own private space 1 mile from downtown Carrboro. Brand new Queen bed and memory foam mattress. Main house in front is also an airbnb that sleeps 6 if you need more space! Lots of charm and much more privacy than a hotel room!

Guest favorite

Guesthouse in Hillsborough

4.99 out of 5 average rating, 266 reviews

Relocated 1915 Cottage in Historic Downtown Hillsborough

Sit out on a front porch rocker facing the Eno River. This property was saved from demolition, disassembled, moved, and restored in 2018. Most of its historic structure remains, including heart pine floors, original shiplap, and cathedral ceilings.

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Durham guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

Guesthouse in Durham

4.87 out of 5 average rating, 186 reviews

Rockwood Oasis Studio BR Full Bath no kitchen

Guest favorite

Guesthouse in Five Points

4.98 out of 5 average rating, 97 reviews

Charming Cottage House in Historic Raleigh

Guest favorite

Guesthouse in Cary

4.92 out of 5 average rating, 318 reviews

Central to Everything, Renovated, Dog Friendly.

Private room in Chapel Hill

Serenity Room 12 min. from UNC

Guest favorite

Guesthouse in Rougemont

4.9 out of 5 average rating, 199 reviews

Cozy Cottage on a Hilltop

Guest favorite

Guesthouse in Raleigh

4.98 out of 5 average rating, 971 reviews

Walk to downtown. Private stylish studio cottage.

Guest favorite

Guesthouse in Chapel Hill

4.96 out of 5 average rating, 359 reviews

Cozy Secluded Accessible West Wing

Guest favorite

Guesthouse in Carrboro

4.96 out of 5 average rating, 69 reviews

Seomra Guestsuite in Carrboro

Show all

Guest house rentals with a patio

Guest favorite

Guesthouse in Fuquay-Varina

5 out of 5 average rating, 57 reviews

Sunset Studio near Downtown Fuquay Varina

Guest favorite

Guesthouse in Chapel Hill

5 out of 5 average rating, 60 reviews

Carolina Cottage

Guest favorite

Guesthouse in Raleigh

4.87 out of 5 average rating, 175 reviews

Retreat La Cabana

Guest favorite

Guesthouse in North Hills

5 out of 5 average rating, 64 reviews

Stylish Sanctuary with Private Garden & Parking

Guest favorite

Guesthouse in Five Points

5 out of 5 average rating, 67 reviews

The Nest: Private Downtown Guest House

Guest favorite

Guesthouse in Mebane

4.96 out of 5 average rating, 45 reviews

Mebane Guest House

Guest favorite

Guesthouse in North Raleigh

4.98 out of 5 average rating, 48 reviews

Carriage House Studio in Quiet Neighborhood

Superhost

Guesthouse in Wake Forest

Couple's Retreat (Attached Guesthouse)

Show all

Guest house rentals with a washer and dryer

Guest favorite

Guesthouse in Cary

5 out of 5 average rating, 131 reviews

Guest House on the Cary Downtown Park!

Guest favorite

Guesthouse in Pittsboro

4.97 out of 5 average rating, 35 reviews

The Sacred Cedar

Guest favorite

Guesthouse in Raleigh

4.93 out of 5 average rating, 92 reviews

The Rose Garden Retreat - NC State/Cameron Village

Guest favorite

Guesthouse in Downtown Durham

4.96 out of 5 average rating, 68 reviews

Duplex filled with natural light

Guest favorite

Guesthouse in North Raleigh

4.97 out of 5 average rating, 62 reviews

The Little Oak City Sanctuary. Centrally Located

Guest favorite

Guesthouse in Raleigh

4.99 out of 5 average rating, 157 reviews

Modern Retreat near Downtown Raleigh

Guest favorite

Guesthouse in Southeast Raleigh

4.88 out of 5 average rating, 48 reviews

Family Friendly 2 bedroom 1 bath apartment

Guest favorite

Guesthouse in Durham

5 out of 5 average rating, 77 reviews

Delightfully Durham: Guesthouse with Kitchen!

Show all

Quick stats about guesthouse rentals in Durham

Total rentals
40 properties
Total number of reviews
3.8K reviews
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
40 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
Local attractions
Durham Bulls Athletic Park, Brier Creek Commons, and Sarah P. Duke Gardens

Guesthouse vacation rentals in Durham

Top-rated guesthouse rentals in Durham

Vacation rentals for every style

Cottages

Apartments

Houses

Popular amenities for Durham guesthouse rentals

Family-friendly guest house rentals

Guesthouse in Durham

Guesthouse in Five Points

Guesthouse in Cary

Private room in Chapel Hill

Guesthouse in Rougemont

Guesthouse in Raleigh

Guesthouse in Chapel Hill

Guesthouse in Carrboro

Guest house rentals with a patio

Guesthouse in Fuquay-Varina

Guesthouse in Chapel Hill

Guesthouse in Raleigh

Guesthouse in North Hills

Guesthouse in Five Points

Guesthouse in Mebane

Guesthouse in North Raleigh

Guesthouse in Wake Forest

Guest house rentals with a washer and dryer

Guesthouse in Cary

Guesthouse in Pittsboro

Guesthouse in Raleigh

Guesthouse in Downtown Durham

Guesthouse in North Raleigh

Guesthouse in Raleigh

Guesthouse in Southeast Raleigh

Guesthouse in Durham

Quick stats about guesthouse rentals in Durham

Total rentals

Total number of reviews

Rentals with dedicated workspaces

Wifi availability

Popular amenities

Local attractions

Destinations to explore