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House vacation rentals in Duck Key

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Top-rated house rentals in Duck Key

Guests agree: these houses are highly rated for location, cleanliness, and more.

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A spacious living area features a light grey sectional sofa adorned with decorative pillows. A flat-screen TV is mounted on the wall, alongside a light-colored media console showcasing various decorative items. In the background, wooden cabinets and a dining area are visible, enhancing the welcoming ambiance.

Home in Key Largo

4.95 out of 5 average rating, 129 reviews

Mariners Club Resort, Best in the Upper Keys

SPACIOUS AND STUNNING Family Friendly 4+ br home. One of the few to allow 10 guests! POOLS w/ hot tubs MARINA for direct access to reef; diving, snorkeling, fishing & sandbars KAYAKING Pennekemp DISCOUNT to swim with dolphins at DPMMR ACTIVITIES; tennis & pickleball courts, gym & game room. LOCATION: restaurants, bars, grocery and other conveniences PARKING for two cars on site WE ARE LOCALS who know the importance of family time so look no further than this special slice of paradise!

Top guest favorite

A serene view of a canal populated by several pelicans floating on the water's surface. Palm trees line the shore, and colorful houses are visible in the background. A boat is docked nearby, enhancing the peaceful coastal scene.

Home in Key Colony Beach

4.98 out of 5 average rating, 104 reviews

Waterfront House with 37 ft Dock & Cabana Club

Right in the middle of the action between Miami and Key West. This 2/2 house has been nicely renovated and furnished with new stainless kitchen appliances and a gorgeous granite countertop. Comfortable outside/inside living space perfect for a getaway in paradise. Walk out to the porch and backyard, and you will be engulfed by the beauty of the sunset views while lying on the cozy hammock. It features lots of outdoor entertaining: fishing, paddling, BBQ or just plain hanging out in the shade.

A modern living area features a spacious white sectional sofa adorned with blue and green decorative pillows. A wooden dining table with white chairs is positioned nearby. Above, a stylish fan circulates air while artwork in calming hues decorates the walls, complementing the light wood flooring.

Home in Key Largo

4.91 out of 5 average rating, 101 reviews

New Oceanside Casa Azul! Voted #1! Golf Cart-Beach

No hidden fees! Casa Azul blends luxury and laid-back island vibes in the heart of Key Largo. With Superhost status and hundreds of 5-star reviews, a perfect escape. Voted the #1 Vacation Rental in Key Largo, it’s ideal for families, couples, and groups alike. Enjoy a free golf cart, fast Wi-Fi, 2 pools, private beach, saltwater lagoon, kayaks, tennis and pickleball courts with gear, marina access, boat ramp, trailer parking, and optional slip rentals. Salt Life meets luxury - this is the one.

The exterior of the house features a vibrant yellow façade with blue accents. A wooden staircase leads to a screened-in porch, while shaded areas beneath the house are furnished with comfortable seating. Lush greenery and palm trees enhance the coastal atmosphere.

Home in Marathon

4.9 out of 5 average rating, 31 reviews

Oceanview Oasis! Screened Porch & Outdoor Theater

Getaway to Paradise in Sunny Marathon! Furnished in comfort and opulence, this private, well-appointed 2 bed 2 bath house boasts: +5-Star OCEANVIEWS +Cozy Screened-in Porch +Outdoor Theater +Jumbo Nest Chairs over lush beach sand +Shade and Sun Loungers +Full Kitchen +Electric Smoker Grill Ready for Adventure? 5 Minutes from the Keys' best public sandy beaches (Sombrero and Bahai Honda State Park), Theater of the Sea, Marathon Aquarium, Dolphin Research Ctr, Turtle Hosp'l and 7-Mile Bridge!

A modern two-story home features a clean white exterior with navy blue accents. A set of black stairs leads to a covered balcony adorned with potted plants. Large windows allow natural light to enter, while a gravel driveway provides ample space in front.

Home in Marathon

5 out of 5 average rating, 34 reviews

Waterfront Escape -VACA-23-408

Come stay at this brand new home construction on a deep and wide canal leading to the ocean with pool and exotic decor. 75 foot dock with water and electric. Top of the line appliances with a fully stocked kitchen. Spa style showers with high end decor. Luxury at its best. Heated pool with sundeck and lots of seating around the edges. (Pool heater is an additional $100 per stay). Ground level cooking and dining for those beautiful days after boating or while laying around in the pool.

Home in Key Colony Beach

4.95 out of 5 average rating, 112 reviews

Waterfront Home 37.5-ft dock, Cabana Club Included

Bright, Open Floor Plan with new floors & kitchen. East facing for sunny mornings and shady afternoons on the great screened porch. Two roomy bedrooms and 2 full baths. Plenty of parking on the paved driveway. Perfectly located with the boater and angler in mind on a 37. 5 ft concrete dock, on deep & wide canal. Here on Key Colony Beach you can walk or bike the entire city to the marina, Sunset Park, 3 restaurants, play golf, tennis, pickle ball, bocce ball, horseshoes & basketball.

A wooden bar area with a tropical theme is visible, featuring a flat-screen TV mounted on the wall. Natural light filters through a nearby enclosure, complemented by bamboo ceiling elements. Decorative accents include a parrot figure and tropical plants, enhancing the inviting space.

Home in Key Largo

4.9 out of 5 average rating, 105 reviews

Sunsets In Palms Paradise

Vacation Rental Permit #19300755 Sunsets in Palms’ Paradise is a waterfront Keys home where you can spend quality time with your family/friends. Our enhanced cleaning practices are as recommended by AIRBNB/CDC, ensuring a sanitary vacation rental safe from Covid-19. Also, this home is the perfect place to vacation if you require social distancing! Features include spectacular sunsets & dolphins for neighbors! Enjoy one acre of privacy and coconut palms galore! VRBO #4648063

A serene outdoor seating area is surrounded by lush greenery. Two hanging chairs with soft cushions face a decorative table. A patterned chair adds to the cozy atmosphere. The space is enhanced by a vibrant green rug, creating a comfortable and inviting retreat.

Home in Key Largo

4.93 out of 5 average rating, 122 reviews

Little Cottage on an island

Very nice quiet neighborhood. Clean updated home with new appliances. Owner does live on property. There is a shared washer/dryer outside. The house is fully furnished with a queen bed and pullout sofa bed twin size. The home has a beautiful little office to work in and a full kitchen with all dishes and cooking utensils. Centrally located in Key Largo... 1 mile away from everything you need! There is a 21 yrs and over policy - house does have liquor bar. Thank you! 🏝️😊

A renovated house is set on a corner lot, surrounded by palm trees and coral stone landscaping. The exterior features light yellow walls and white accents. A gravel driveway offers ample parking space, complementing the tranquil tropical environment.

Home in Marathon

4.92 out of 5 average rating, 136 reviews

Marathon Star - home with hot tub

Completely renovated 3 bedroom house in Marathon. Conveniently located near the Florida Keys Aquarium Encounters and the Marathon Lady. Enjoy a private hot tub and outdoor grill after a long day of Florida sunshine! Our home is not on the water but there is plenty of parking space for your boat trailer if needed. We hope our wonderful space becomes a great home away from home. ***Please see below for more information regarding hurricane season cancellation policy.

Top guest favorite

A spacious balcony features several green patio chairs arranged along the wooden floor. The view overlooks the shimmering water, while palm trees sway in the background under a clear blue sky. The balcony is protected by a white railing, enhancing the outdoor space.

Home in Marathon

4.94 out of 5 average rating, 53 reviews

Paradise Found! Oceanfront home & amazing sunrises

License :VACA-22-182 Escape to our tropical oasis in the Florida Keys! Our vacation house offers a whimsical adventure with fantastic outdoor amenities: balcony, charcoal grill, private pool/spa, hammock, outdoor furniture, and an outdoor freezer for your catch. Stay connected with high-speed internet, enjoy entertainment with a Smart TV and iPhone dock, and rest assured with outdoor security cameras. Book now for an extraordinary getaway!

A covered walkway features wooden beams and a textured privacy screen. Two white rocking chairs are placed on a composite deck, accompanied by a decorative lantern. Soft lighting strung above creates a serene atmosphere, with views of the water visible in the distance.

Home in Key Largo

4.97 out of 5 average rating, 101 reviews

The Paradise 2

Relax with the whole family at this peaceful place to stay. Our home is located right by the water. Modern spacious and spotless with private parking, fast Wi-Fi, cold AC plus cozy beds and pillows in every bed. Relax on the waterfront patio chairs, swim in our newly renovated pool, watch the manatees and dolphins swim by and go fishing from our backyard dock anytime. We are sure you will absolutely love our Tiny Home!

The exterior of a blue house is surrounded by a landscaped garden featuring palm trees and other greenery. A gravel driveway leads to the entrance, providing ample space for parking. The sky is clear and sunny, enhancing the inviting atmosphere of the property.

Home in Marathon

4.93 out of 5 average rating, 115 reviews

Beautiful Renovated Home in Marathon, FL

Cozy home centrally located in the heart of Marathon with a ton of parking space for a boat or RV... Stay at ease in this family friendly neighborhood with lots of fun nearby (within 10 minutes) such as Sombrero Beach, FL Keys Aquarium, public boat ramp, kayaking, diving, restaurants and more!!! Licensed and inspected by the City of Marathon, Lic.#VACA-21-409

Vacation rentals for every style

Get the amount of space that is right for you

Villas

Luxurious estates for the ultimate escape

Apartments

Convenient locations with everyday essentials

Hotels

Stylish accommodations and amenities

Popular amenities for Duck Key house rentals

Free parking on premises

Air conditioning

House rentals with a pool

Top guest favorite

Home in Marathon

4.99 out of 5 average rating, 132 reviews

Sea Ray Cove, Mini Lobster week NOW OPEN!

Home in Key Largo

4.94 out of 5 average rating, 69 reviews

Casa Solaris | Key Largo home with Private Pool!

Home in Key Largo

4.86 out of 5 average rating, 100 reviews

Cary’s Oceanside

A spacious kitchen and dining area feature white cabinetry and a large island, providing ample food preparation space. Natural light floods the room through large windows, with a view of palm trees and the water visible in the background. Stools line the island, creating a welcoming atmosphere.

Home in Marathon

4.93 out of 5 average rating, 29 reviews

Serenity Bay Estate-FL Keys Best Kept Secret! Beau

A heated swimming pool is featured in a wooden deck area, surrounded by tropical palm trees. Lounge chairs are positioned for relaxation, while the exterior of the two-story home includes expansive glass doors that provide a view of the inviting pool and canal.

Home in Islamorada

4.86 out of 5 average rating, 7 reviews

Venetian Tropics private heated pool at 82 degrees

Top guest favorite

A private pool is positioned in a landscaped yard, accompanied by an umbrella for shade. The setting features views of a canal, with boats docked nearby, complemented by tropical plants and a light-colored exterior of the duplex.

Home in Key Colony Beach

5 out of 5 average rating, 83 reviews

“La casa azul” step 3’ to a private pool

A spacious living area features a large gray sectional sofa adorned with decorative cushions. A round coffee table is positioned in front, and a colorful painting of a boat enhances the wall. Natural light streams in through glass doors leading to an outdoor seating area.

Home in Marathon

4.88 out of 5 average rating, 24 reviews

Golf Coast Oasis

A spacious dining area features a large white table surrounded by modern chairs, complemented by woven pendant lights. A comfortable sofa is situated nearby, with windows offering natural light and views of the outdoor environment. Coastal decor accents the walls, enhancing the serene atmosphere.

Home in Marathon

4.96 out of 5 average rating, 112 reviews

Anglers Terrace, Condé Nast Traveler's Best Airbnb

Weekly house rentals

The living area showcases light-colored wood flooring and large windows offering views of the surroundings. A sectional sofa and a coffee table with a coastal design create a relaxed seating arrangement. A dining table is positioned nearby, complemented by pendant lighting.

Home in Key Colony Beach

4.74 out of 5 average rating, 23 reviews

Private Beach, Deep Water Dockage, Cabana Club

A tranquil canal scene is depicted, lined with palm trees and private docks. Water reflects the clear blue sky, creating a serene atmosphere. Boats are moored along the canal, showcasing direct access to Gulf and Ocean waters.

Home in Marathon

5 out of 5 average rating, 40 reviews

Yellowtail Getaway with Boat Dock and Pool 2

An outdoor seating area is shown under a large sunshade, with soft lighting suspended above. The scene captures a serene sunset reflecting on the calm canal water, surrounded by palm trees and residential buildings in the background.

Home in Marathon

5 out of 5 average rating, 3 reviews

Sailors Paradise

A kitchen window displays a view of serene canal waters, accompanied by boats docked nearby. Decorative plants are positioned on the countertop, adding a touch of greenery. The sign above the window reads 'Marathon,' providing a local touch to the space.

Home in Marathon

4.91 out of 5 average rating, 69 reviews

Blue Ocean Bungalow Spring discounts-NOW available

A canal dock extends alongside the property, featuring wooden decking and a swimming ladder for easy access to the water. Lounge chairs are positioned nearby, and tall palm trees provide a tropical ambiance. The clear blue sky reflects off the tranquil water.

Home in Key Colony Beach

4.91 out of 5 average rating, 135 reviews

The Snapper House 3/2.5 45' dock sleeps 8+ pets OK

A bright exterior view showcases a charming home perched on the canal's edge. Lush greenery frames the property, while a private dock extends into the water. Sunlight reflects off the calm water, and a blue sky dotted with fluffy clouds enhances the tranquil setting.

Home in Marathon

4.96 out of 5 average rating, 69 reviews

Private 174ft Dock, Boat Launch, Sombrero Beach

A pair of outdoor chairs is positioned on a balcony, overlooking a vibrant canal. Palm trees and neighboring homes line the waterway, while a bright sky filled with fluffy clouds enhances the serene waterfront view.

Home in Cudjoe Key

4.87 out of 5 average rating, 104 reviews

Island Oasis ~ YOUR Paradise Awaits!

A wooden dock extends into a calm canal, surrounded by clear water. Post lights are visible along the dock, and palm trees line the opposite bank. The sky above is partly cloudy, enhancing the tranquil setting.

Home in Key Colony Beach

4.86 out of 5 average rating, 7 reviews

Seas the Day

Private house rentals

A modern beach house exterior features a spacious courtyard surrounded by light-colored gravel. A hot tub and shaded seating area with an umbrella are visible, along with a pergola and a cozy lounge setup. Palm trees provide a tropical backdrop, enhancing the outdoor space.

Home in Marathon

5 out of 5 average rating, 17 reviews

Seaside Sunrise. Newly remodeled waterfront

Top guest favorite

An open living area showcases a modern design with white wood beams and bright walls. A dark granite countertop separates the dining area from the lounge, furnished with blue seating and a flat-screen TV. Large glass doors provide views of the outdoor space.

Home in Key Colony Beach

5 out of 5 average rating, 44 reviews

Florida Keys Retreat / Completly remodeled

Top guest favorite

A screened terrace offers views of the canal and marina, showcasing several boats docked nearby. Two seating areas are visible, featuring a sofa and two chairs with bright yellow cushions. The floor is tiled, and sunlight illuminates the outdoor space.

Home in Key Largo

4.91 out of 5 average rating, 167 reviews

Blue House Marine in Key Largo

A modern living area features comfortable black reclining sofas and a light-colored coffee table with woven storage underneath. A large flat-screen TV is mounted on a white media console, and vibrant turquoise walls enhance the bright and airy atmosphere.

Home in Marathon

4.98 out of 5 average rating, 91 reviews

4BR 3B, Heated Pool & Spa, 60' Dock

Home in Key Colony Beach

4.94 out of 5 average rating, 49 reviews

Waterfront House - 30' Dock & Pool & Cabana Club

A view from the balcony showcases a serene canal lined with palm trees and residential homes. The water reflects the clear blue sky, creating a tranquil atmosphere. The balcony features white railings, inviting relaxation and enjoyment of the surrounding scenery.

Home in Key Colony Beach

4.95 out of 5 average rating, 42 reviews

Casa Lago Mar 3/2 with Cabana Club Access

A calm waterway is flanked by thatched-roof structures on either side, surrounded by lush palm trees. The clear blue sky reflects on the still water, establishing a serene atmosphere. The scene invites opportunities for boating and leisure activities.

Home in Key Largo

4.8 out of 5 average rating, 92 reviews

Paradise Found-Key Largo Kampground Divers Welcome

Top guest favorite

A dining area features a round table surrounded by wicker chairs, highlighted by a vase of vibrant flowers. The blue walls complement the mirrored decor, while large glass doors offer access to a balcony overlooking the waterway and surrounding landscape.

Home in Key Largo

4.89 out of 5 average rating, 123 reviews

Paradise Palace 3/3 Waterfront Pool Kayak 60' Dock

Quick stats about house rentals in Duck Key

Total rentals
50 properties
Nightly prices starting at
$120 before taxes and fees
Total number of reviews
1.3K reviews
Family-friendly rentals
50 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with a pool
30 properties have a pool

Destinations to explore