House vacation rentals in Des Moines
Find and book unique houses on Airbnb
Top-rated house rentals in Des Moines
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Des Moines house rentals
House rentals with a pool
Home in Ankeny
4.85 out of 5 average rating, 124 reviewsFive Star Modern Farmhouse Indoor Hot Tub for 8.
Home in West Des Moines
4.98 out of 5 average rating, 40 reviewsCute West Des Moines Guest House
Home in Ankeny
4.98 out of 5 average rating, 80 reviewsHistoric Home on 4 Acres - Hot Tub, Pool, Tiki Bar
Home in Des Moines
4.88 out of 5 average rating, 40 reviewsUrban Oasis: Cozy Gathering Spot/Retreat - Hot Tub
Home in Grimes
5.0 out of 5 average rating, 55 reviewsSleeps 12, Spacious, Family Friendly (w/ Pool!)
Home in Urbandale
4.9 out of 5 average rating, 21 reviewsThe Estate
Home in Ankeny
4.85 out of 5 average rating, 34 reviewsComfortable and Spacious Five Bedroom Home
Home in Ankeny
4.97 out of 5 average rating, 31 reviewsQuiet newer townhome neighborhood
Weekly house rentals
Home in Des Moines
4.93 out of 5 average rating, 194 reviewsFully Fenced Story Book Cottage, close to downtown
Home in Ankeny
4.94 out of 5 average rating, 124 reviewsNewly Remodeled Home with Walk-In Shower
Home in Des Moines
4.88 out of 5 average rating, 150 reviewsCharming Des Moines Home with a GREAT location!
Home in Des Moines
4.88 out of 5 average rating, 385 reviewsGarden Retreat Near Downtown
Home in Des Moines
4.9 out of 5 average rating, 612 reviewsSteps to Drake, Minutes to Downtown w Patio+Yard!
Home in Des Moines
4.95 out of 5 average rating, 149 reviewsWhole House Near I-80/35, Downtown, Fairgrounds
Home in Indianola
4.99 out of 5 average rating, 147 reviewsThe Hen House
Home in Des Moines
4.84 out of 5 average rating, 152 reviewsCharming 4 Bedroom Home With Beautiful Backyard
Private house rentals
Home in Des Moines
4.97 out of 5 average rating, 58 reviewsElegant Home that's Fully Fenced and Pet Friendly
Home in Des Moines
4.93 out of 5 average rating, 101 reviewsCozy Bungalow Home-Central Des Moines
Home in Des Moines
4.98 out of 5 average rating, 86 reviewsMidCentury, technicolor Ranch w/yard, w+d, parking
Home in Waukee
4.98 out of 5 average rating, 40 reviews2 Bed 2 Bath
Home in Des Moines
4.97 out of 5 average rating, 35 reviewsCozy Cute Bungalow
Home in Des Moines
5.0 out of 5 average rating, 16 reviewsSingle Family w/ King Bed - Large Yard - Near DSM
Home in Des Moines
5.0 out of 5 average rating, 88 reviewsRestored Victorian, Walk & Bike
Home in Cumming
4.97 out of 5 average rating, 37 reviewsLittle Shouse On The Prairie
Quick stats about house rentals in Des Moines
Total rentals
360 properties
Wifi availability
360 properties include access to wifi
Rentals with dedicated workspaces
230 properties have a dedicated workspace
Pet-friendly rentals
150 properties allow pets
Family-friendly rentals
250 properties are a good fit for families
Total number of reviews
18K reviews
Destinations to explore
- Ames Vacation rentals
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- Family travel hub Tips and inspiration
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