Vacation rentals in Clayton

Book unique vacation rentals, houses, and more on Airbnb

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Popular amenities for Clayton vacation rentals

Stay near Clayton's top sights

Delmar Loop142 locals recommend
Saint Louis Zoo579 locals recommend
St. Louis Galleria146 locals recommend
Salt + Smoke95 locals recommend
Blueberry Hill73 locals recommend
Fitz's48 locals recommend

Other great vacation rentals in Clayton

Superhost
Home in Florissant
5 out of 5 average rating, 3 reviews

Florissant's Old Town Inn (3BR)

HelenRating, 5 stars8 months ago
What a treasure we stumbled across! If you enjoy the vibes of an older home this one is for you! The neighborhood is very safe and amazing! The actual home has glass door knobs (if you know you know). The antique ceiling lights are amazing. They do have electronic locks, which are easy to access. The baths are updated, as well as the kitchen. Everything you could need was provided. We rented the entire place, (upstairs and down). My husband and I enjoying a weekend to watch some Cardinals baseball with our two adult children and a granddog. Sitting on the back patio watching the Koi fish could not have been more relaxing. Thanks for a great adventure. I hope to be able to visit this home in the future.
Superhost
Home in Ballwin
4.83 out of 5 average rating, 24 reviews

Becky's Oasis-Sleeps 6/3 beds/Ballwin MO

BrannonRating, 5 stars4 months ago
Becky was very helpful and responsive. The house was convenient to the airport and nearby shopping.
Top guest favorite
A stylish bar area is presented with four black, cushioned stools set around a granite-topped counter. The backdrop features warm wooden paneling that complements the sleek black brick base, creating a modern yet cozy atmosphere.
Home in Ballwin
5 out of 5 average rating, 30 reviews

Perfect Getaway 3BR/3BA Home

BlakeRating, 5 stars2 days ago
Wonderful stay. The place was easy to access and exactly as described. The host was friendly and responsive. Would definitely stay again.
Guest favorite
The exterior of a tranquil retreat is framed by lush greenery and vibrant flower beds. A gravel path leads to the building, which features a sloped roof and large windows. The surrounding landscape includes various plants, contributing to the peaceful environment.
Cottage in Sugar Loaf Township
4.92 out of 5 average rating, 71 reviews

Cheerful one bedroom cottage on a horse farm

SavannahRating, 5 stars2 months ago
It was so nice to get away and relax for the night at the cottage! It was so peaceful! Water pressure in the shower was amazing and the bed was so comfortable! Will definitely stay again!
Guest favorite
Apartment in St. Louis
4.87 out of 5 average rating, 301 reviews

We do Italian STL style. Perfecto! Enjoy our NBHD!

AmyRating, 5 stars4 weeks ago
This was the perfect spot… peaceful, safe, and quiet neighborhood within walking distance of so many homey, welcoming local restaurants! It was lovely to be able to walk everywhere to dinner and not have to drive. And it was within easy driving distance of all the tourist stuff we wanted to do. The suite had everything we needed and we especially appreciated the labels on the light switches! Very clean and comfy. Would 100% stay here again.
Superhost
Home in St. Louis
4.82 out of 5 average rating, 66 reviews

Modern Luxury w/Saltwater Pool / ABODEbucks

BrandonRating, 5 stars2 weeks ago
Had a wonderful stay at this Airbnb! The place was exactly as described—clean, comfortable, and thoughtfully decorated. The host was incredibly welcoming and responsive, making sure everything went smoothly. The location was perfect for exploring the area, and I truly felt at home during my stay. I would absolutely stay here again and highly recommend it to anyone looking for a relaxing and enjoyable visit! The work room was a plus.
Guest favorite
An open concept living area is framed by elegant wooden columns, leading to a dining space with a large table and stylish chairs. Natural light streams through a window, highlighting the warm wood tones of the floors and the subtle decor within the space.
Home in Lindenwood Park
4.86 out of 5 average rating, 735 reviews

Centrally Located Family Home - Park Like Yard

GeorgiaRating, 5 stars3 weeks ago
One of the best places that I've ever stayed! It was excellent! Will stay again, if needed!
Superhost
A tranquil pond is surrounded by lush greenery, reflecting the nearby trees. A fallen log rests at the edge of the water, while gentle ripples disturb the calm surface. The serene landscape offers a peaceful retreat in the nature-filled setting.
Cottage in Saint Charles
5 out of 5 average rating, 31 reviews

Quiet St Charles Cottage w/ Patio & 4 Acres

Monica Rating, 5 stars15 months ago
Had a great stay here, was very warm and cozy plenty of space especially if you’re traveling alone… Anita was very useful with plenty of instructions and great communication about the property.. I would highly recommend a stay here

Quick stats about vacation rentals in Clayton

  • Total rentals

    30 properties

  • Nightly prices starting at

    $50 before taxes and fees

  • Total number of reviews

    1.4K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

Frequently Asked Questions

  • Where should I stay in Clayton?

    Make yourself at home in Clayton by choosing from our most frequently booked neighborhoods. We have over 310 vacation rentals in Wydown Skinker, and over 310 vacation rentals in Downtown Clayton.

  • How much does it cost to stay in apartment rentals in Clayton?

    Experience the best of Clayton with our apartment rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there apartment rentals with a dedicated workspace in Clayton?

    Yes! Work meets play with ease at over 10 apartment rentals in Clayton featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there pet-friendly vacation rentals in Clayton?

    Four-legged friends are welcome in Clayton. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Do apartment rentals in Clayton have wifi?

    Absolutely! We offer over 20 apartment rentals with wifi in Clayton. Enjoy a tailored experience with all the comforts you desire.

  • Are there family-friendly apartment rentals in Clayton?

    Clayton has more than 10 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

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