Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 215 reviewsBungalow Under The Oaks
Guesthouse in North Charleston
5.0 out of 5 average rating, 112 reviewsThe Park Circle Clerestory Studio Guest House
Guesthouse in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
Guesthouse in Charleston
4.91 out of 5 average rating, 650 reviewsIsland Oasis—Near Downtown
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in North Charleston
4.86 out of 5 average rating, 443 reviewsPark Circle Jungalow Loft
Guesthouse in Summerville
4.94 out of 5 average rating, 213 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 224 reviewsGreen Garden Studio @greengardenstudio2017
Guest house rentals with a patio
Guesthouse in Johns Island
4.91 out of 5 average rating, 108 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Charleston
4.98 out of 5 average rating, 124 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Charleston
4.97 out of 5 average rating, 129 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Hanahan
4.99 out of 5 average rating, 79 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 80 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Goose Creek
4.96 out of 5 average rating, 50 reviewsThe Blue Secret
Guesthouse in Charleston
5.0 out of 5 average rating, 14 reviewsLowcountry Guesthouse
Guesthouse in Mount Pleasant
4.9 out of 5 average rating, 20 reviewsAdorable guest house with private backyard/patio
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.99 out of 5 average rating, 145 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Charleston
4.9 out of 5 average rating, 552 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 258 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
5.0 out of 5 average rating, 218 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 438 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 249 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 252 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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