Guesthouse vacation rentals in Mount Pleasant
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Top-rated guesthouse rentals in Mount Pleasant
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mount Pleasant guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 100 reviews5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in North Charleston
4.94 out of 5 average rating, 350 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.92 out of 5 average rating, 308 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Mount Pleasant
4.85 out of 5 average rating, 223 reviewsClose to beach , downtown and Shem creek
Guesthouse in Summerville
4.98 out of 5 average rating, 651 reviews★Delightful guest house near historic plantations★
Guesthouse in Charleston
4.93 out of 5 average rating, 712 reviewsCharleston's Coolest Neighborhood
Guesthouse in Charleston
4.91 out of 5 average rating, 654 reviewsIsland Oasis—Near Downtown
Guesthouse in Summerville
4.94 out of 5 average rating, 215 reviewsNina's Cottage -Historic Downtown Summerville
Guest house rentals with a patio
Guesthouse in Charleston
4.93 out of 5 average rating, 178 reviewsQuaint Cottage Studio in Ashley Forest (Avondale)
Guesthouse in Charleston
4.98 out of 5 average rating, 128 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Charleston
4.96 out of 5 average rating, 132 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Johns Island
4.91 out of 5 average rating, 113 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Hanahan
4.99 out of 5 average rating, 84 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Mount Pleasant
4.9 out of 5 average rating, 21 reviewsAdorable guest house with private backyard/patio
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 77 reviews*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 30 reviewsCoastal Charm: Village Hideaway
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.9 out of 5 average rating, 554 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Summerville
4.97 out of 5 average rating, 221 reviewsTiny Oak Cottage in Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 254 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Guesthouse in Charleston
4.99 out of 5 average rating, 210 reviewsRedesigned suite! 12min to city, pet-friendly
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 100 reviewsPrivate Cottage in Southern Mt. Pleasant, SC
Guesthouse in Charleston
4.98 out of 5 average rating, 246 reviewsDetached Guest Suite
Guesthouse in Charleston
5.0 out of 5 average rating, 222 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Charleston
4.99 out of 5 average rating, 150 reviewsLarge Guesthouse with Private Dock & Marsh Views
Quick stats about guesthouse rentals in Mount Pleasant
Total rentals
60 properties
Popular amenities
Kitchen, Wifi, and Pool
Wifi availability
60 properties include access to wifi
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
5.7K reviews
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