Mansion vacation rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Mansion rentals with a pool
Apartment in Panama City
4.9 out of 5 average rating, 30 reviewsPenthouse deluxe, 360º views and glass pool
Home in Playa Bluff
5.0 out of 5 average rating, 16 reviewsJungle House 100m from the beach
Apartment in San Carlos District
4.99 out of 5 average rating, 79 reviewsAmazing Oceanfront apartment in San Carlos
Cottage in Altos del Maria
4.93 out of 5 average rating, 99 reviewsCabin with Spectacular Mountain View
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Apartment in Panamá
5.0 out of 5 average rating, 21 reviewsTop Floor Condo 6 bedroom with amazing views
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Condo in Maria Chiquita
5.0 out of 5 average rating, 19 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Luxury mansion rentals
Villa in Punta Chame
4.92 out of 5 average rating, 13 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Apartment in Maria Chiquita
5.0 out of 5 average rating, 6 reviews4 recamaras Playa Escondida
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
Villa in Río Hato
4.92 out of 5 average rating, 73 reviews(Panama) Beach house with golf course.
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
Home in Coronado
4.7 out of 5 average rating, 20 reviewsCHARMING ALMAR FRONT HOUSE WITH PISCINA-CORONADO
Cabin in Panama
4.92 out of 5 average rating, 12 reviewsCasa de Playa Portobelo Caribe
Home in Bajo Boquete
4.77 out of 5 average rating, 65 reviews7 sketch mountain Jaramillo house upstairs Boquete
Pet-friendly mansion rentals
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Condo in San Carlos District
4.97 out of 5 average rating, 37 reviewsPunta Caelo Beach Front View
Home in San José
5.0 out of 5 average rating, 18 reviewsαlkeyler| Luxury Mini Resort 12 PERS @Punta Barco
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Villa in Costa Esmeralda
4.97 out of 5 average rating, 70 reviews#1 Villa with pool, jacuzzi, pool table, ping pong.
Villa in Costa Esmeralda
5.0 out of 5 average rating, 13 reviewsSpectacular 600-meter oceanfront beach house
Apartment in El Chirú
4.94 out of 5 average rating, 84 reviewsBuenaventura Golf & Beach Resort Lux Apartment
Home in Río Hato
4.98 out of 5 average rating, 96 reviewsComplete House for a Perfect Stay
Destinations to explore
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