Vacation rentals in Isthmus of Panama

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Top-rated vacation rentals in Isthmus of Panama

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Cabin in Torio

4.97 out of 5 average rating, 103 reviews

Cozy open space, unique jungle views, river access

Casa Corotu is located in Torio Hills a 10 minute's walk to the beach with a a trail to access Torio river. Fiber Optic WiFi and two work spaces. The property surrounded by big trees that keep the house cool, which also provide shelter for birds and wildlife. The house is NOT childproof, minimal railing system. It's a great house to live the experience of #toriolife and all it has to offer. It is also an opportunity to experience the jungle in an open-style home with a mesmerizing treetop view.

Guest favorite

Cottage in Bocas del Toro Province

4.96 out of 5 average rating, 174 reviews

Rustic cottage-Ocean views/walk to surfing/Jungle

Casa Palmera is located near the only beach to the north/west side of Isla Carenero, with a beautiful ocean view where the sun sets in a secluded and peaceful area. Only a 5 minute walk to the Carenero Surf Break . Restaurants are within walking distance, hike around the island, or use the kayaks and see the beauty. We are 5 minute boat taxi away from the main town of Bocas, but everything you need to make your vacation unforgettable is on this island! Drinking water included.A/C in bedrooms

Guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 112 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Guest favorite

Home in Costa Esmeralda

4.96 out of 5 average rating, 107 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sand! Come relax with the whole family at this piece of paradise. Majestic Sand is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool with multiple hammocks with views of amazing palm trees.

Superhost

Earthen home in El Cope, Penonome

4.91 out of 5 average rating, 147 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

Guest favorite

Guesthouse in La Ermita de San Carlos

4.97 out of 5 average rating, 108 reviews

Sky Cabin/Beaches/Pool/Surf/Digital Nomads

The Sky Cabin is part of 5 cabins “A Piece of Paradise” With registration in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and kitchen ✸ Spacious terrace with a hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing) ✸ Breakfast for an additional $7.00, for each guest.

Guest favorite

Loft in Panamá

4.91 out of 5 average rating, 182 reviews

Amazing Loft with the Best view of Casco viejo!

Hermoso loft ubicado en el centro de Casco Antiguo, la zona más turística de Panamá. Ven, disfruta y relájate en este impresionante loft, con una vista increíble de la Catedral de Panamá. Puedes visitar museos, bares, restaurantes e iglesias ubicados a tan solo unos cuantos metros de distancia. Beatiful Loft located in the center of Casco Antiguo, Panama´s most turistic location. Come, enjoy and relax at this amazing loft, with amazing view to Panama´s Cathedral.

Guest favorite

Home in Taboga Island

4.96 out of 5 average rating, 141 reviews

Casa Rosie - Taboga dream home

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite

Hut in Cristóbal Island

4.94 out of 5 average rating, 123 reviews

Cocovivo Bioluminescent Coconut

Strategically placed to catch the sunset, this airy waterfront cabin is designed for ultimate relaxation. Perfect for sun bathing, sunset gazing and when night falls, strong bioluminescent waters makes this cabin seem like it's out of a fairy tale. A coral reef aligns the whole property for world-class snorkeling, kayak or SUP expeditions! Jetsons-meet-Flintstones" is the vibe here. Please read the “Other things to note” section so you know what to expect!

Guest favorite

Apartment in Panamá

4.94 out of 5 average rating, 36 reviews

Apart from full luxury studio in Panama.

Located in San Francisco, one of the quintessential exclusive areas in Panama, where gastronomy, history, modernity and entertainment are magically combined. Wonderful location close to must-see destinations, gym, swimming pool, coworking, pet spa and terrace. The parking lot is charged. Modern and functional, this apartment features a queen bed room, fully equipped kitchen, Wifi, TV, a spectacular balcony with ocean views, laundry center and sofa bed.

Superhost

Home in Playa Venao

4.9 out of 5 average rating, 115 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.

Superhost

Treehouse in Isla Colon

4.95 out of 5 average rating, 133 reviews

Secret Jungle Treehouse by the Sea

A 2 bedroom treehouse built around a huge tree overlooking the lush jungle in a hidden setting. Artistically designed & comfortable; welcoming romantic souls, nature lovers & the adventurous. Enjoy nature in the harmony of an eco environment; ocean breezes, sound of waves, birds & monkeys. Spectacular sandy beaches only steps away. Surf, swim, bike, explore & live the adventure!. YouTube « Jungle Treehouse by the sea »