Mansion vacation rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama mansion rentals
Mansion rentals with a pool
Home in Buenaventura, El Chirú
5 out of 5 average rating, 5 reviewsBeachfront | Luxury & Style | 70% OFF! | King Beds
Home in Río Hato
4.95 out of 5 average rating, 76 reviewsSpectacular beachfront house in Buenaventura!
Villa in Panamá
4.98 out of 5 average rating, 50 reviewsBeautiful House in Panama w/ King Beds + Pool
Villa in Portobelo
5 out of 5 average rating, 44 reviewsEntire Villa with pool in front of beach!
Home in Playa Bluff
4.95 out of 5 average rating, 19 reviewsJungle House 100m from the beach
Home in San Carlos
4.93 out of 5 average rating, 90 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Rental unit in Panamá
5 out of 5 average rating, 23 reviewsTop Floor Condo 6 bedroom with amazing views
Condo in Maria Chiquita
5 out of 5 average rating, 24 reviewsPlaya Escondida Lux Beachfront Haven:Oceanview Apt
Luxury mansion rentals
Rental unit in Panama City
4.69 out of 5 average rating, 251 reviewsPenthouse with rooftop and pool 5 rooms Di5
Rental unit in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPenthouse in Playa Escondida 4 bedrooms
Villa in Bejuco
4.96 out of 5 average rating, 78 reviewsBeach house in Punta Chame, Villa frente al mar
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
Home in Anton Valley
5 out of 5 average rating, 26 reviewsLovely and Cousy house at El Valle
Home in Bajo Boquete
4.77 out of 5 average rating, 65 reviews7 sketch mountain Jaramillo house upstairs Boquete
Home in Altos del Maria
4.78 out of 5 average rating, 36 reviewsBeauty Mountain House
Villa in Río Hato
4.92 out of 5 average rating, 73 reviews(Panama) Beach house with golf course.
Pet-friendly mansion rentals
Condo in San Carlos District
4.97 out of 5 average rating, 38 reviewsPunta Caelo Beach Front View
Villa in Costa Esmeralda
4.97 out of 5 average rating, 71 reviews#1 Villa with pool, jacuzzi, pool table, ping pong.
Home in San José
4.96 out of 5 average rating, 23 reviewsαlkeyler| Luxury Mini Resort 12 PERS @Punta Barco
Villa in Bocas del Toro
5 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Villa in Costa Esmeralda
5 out of 5 average rating, 16 reviewsSpectacular 600-meter oceanfront beach house
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Villa in Punta Chame
4.92 out of 5 average rating, 13 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Home in Panamá
5 out of 5 average rating, 12 reviewsWonderful House with Terrace and Sea View
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