Vacation rentals in Osborn Medical Center, Phoenix

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Top-rated vacation rentals in Osborn Medical Center, Phoenix

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 126 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Guest favorite

Condo in Encanto

4.91 out of 5 average rating, 114 reviews

The Beverly Bungalow 1BR/BA in the 🖤 of Phoenix

Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2 (up to 4 using our air mattress). Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Guest favorite

Home in Encanto

4.98 out of 5 average rating, 199 reviews

Phoenix Oasis-Great Outdoor Space-No Cleaning Fee!

Perfectly located, this Central Phoenix retreat is a remodeled, immaculately kept, Central Phoenix home built in 1944. It is beautifully furnished with everything you need for a comfortable stay. Included is a relaxing outdoor space to enjoy morning coffee or BBQ dinner. It is on a quiet street on the grand canal, walking distance to the light rail, restaurants, cafes, bars, museums, Steele Indian School Park (one of the largest parks in Phoenix), and all the attractions in downtown Phoenix.

Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 1093 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Guest favorite

Guesthouse in Encanto

4.98 out of 5 average rating, 132 reviews

Private Studio-Sized House in Historic Willo PHX

This safe, centrally-located, stand-alone guest house is nestled in a quiet historic neighborhood. You'll be a 15-min walk to world-class museums as well as a broad range of great bars and restaurants. The Encanto light rail stop at the end of our street is an easy $2 fare. Dog walkers, bicyclists, and migrating birdsong make walks a great way to start your day. 2-night minimum required, studio-sized bathroom, absolutely no parties, pets or commercial photography allowed (fines will follow).

Guest favorite

Guest suite in Encanto

5.0 out of 5 average rating, 229 reviews

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Guest favorite

Guesthouse in Encanto

5.0 out of 5 average rating, 299 reviews

Urban Green House

The Urban Green House brings farm life to the urban core. We offer fresh eggs from our backyard hens and gardens for guests to enjoy. We also live green-using solar panels, recycling, and composting. The hosts live on the property and are available to meet any needs that arise. We are located in a quiet and safe 1950s neighborhood, close to local restaurants, coffee shops, Encanto park, direct access to both the I-10 and I-17 freeways, and only 8 miles from Phoenix Sky Harbor Airport.

Guest favorite

Guesthouse in Encanto

4.99 out of 5 average rating, 118 reviews

PHX's Modern Midtown Carriage House, Free Parking

Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

Guest favorite

Place to stay in Alhambra

4.97 out of 5 average rating, 884 reviews

Uptown Private guest House 1 King Bed Pool/Jacuzzi

“CHECKING IN INSTRUCTIONS”at “GUEST RESOURCES”on Airbnb. PLEASE NO EARLY CHECK-IN due to time constraints. The guest room air conditioner/heater/king size bed/linens/Plates/glasses-all plastic, towels/wifi/premium cable with movies Premium internet. Guest house 275 sq feet There is street parking with parking permit available. NO SMOKING of any products inside guest house Property 420 friendly only in outdoor spaces QUIET HOURS between 10:00 pm-6:00 am. No loud noise

Guest favorite

Guesthouse in Central City

4.95 out of 5 average rating, 925 reviews

Studio B industrial design

A contemporary industrial designed studio with cement floors and exposed pipes. A grey water system irrigates the lush southwest gardens. Be adventurous and choose the outdoor shower in the enclosed back patio to fully appreciate the warm weather! Tucked away in the historic F.Q. Story Neighborhood in downtown Phoenix. You are surrounded by charming historic homes as you walk the neighborhood. Close to local eats, parks, and museums. EVERYONE is welcome at Studio B!

Superhost

Home in Encanto

4.87 out of 5 average rating, 630 reviews

Stroll to Restaurants from a Private, Airy Home

Cook breakfast on the Thermador gas range or sip morning coffee at the glass-top kitchen island. The contemporary home is decorated with cheery Southwestern accents and sleek mid-century furniture under 15-foot vaulted ceilings. Many guests make the short walk to lively Lux Central coffee house just a few minutes away where they can work on laptops or socialize with the business and scene crowd. There is a guest house on the property that is a separate Airbnb.

Guest favorite

Guesthouse in Encanto

4.99 out of 5 average rating, 173 reviews

Adorable Willo Cottage in Historic Central Phoenix

Peaceful one bedroom cottage in unbeatable location within Central Phoenix. Walking/ biking distance from light rail, restaurants, Heard Museum and Phoenix Art Museum. Enclosed backyard with a shared washer/dryer on property. The cottage has a queen bed, mini kitchen and private patio. Property is cleaned and sanitized according to the Airbnb cleaning procedures. 15 minutes from Sky Harbor Airport. 5 minutes from Encanto Park (Golf Course)